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Grade 1 acne is characterized by:

  1. Chronic inflammation of the sebaceous gland

  2. Inflammation and redness

  3. Minor breakouts, some open and closed comedones

  4. Small hard white bumps

The correct answer is: Chronic inflammation of the sebaceous gland

Grade 1 acne is characterized by chronic inflammation of the sebaceous gland. This means that at this level of acne, there is an ongoing inflammation of the sebaceous glands in the skin, which can lead to the formation of non-inflammatory lesions such as open and closed comedones. The other options are incorrect because they do not fully capture the primary characteristic of Grade 1 acne. Inflammation and redness, minor breakouts with open and closed comedones, and small hard white bumps are more commonly associated with other grades of acne, not specifically Grade 1.