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Secondary Lesions are characterized by:

  1. Lesions that develop in the early stages of disease

  2. Lesions that change the structure of tissues and organs

  3. Flat, non-palpable changes in skin color

  4. Black or dark patches on the skin

The correct answer is: Lesions that change the structure of tissues and organs

Secondary lesions are characterized by changes in the structure of tissues and organs. These are alterations to the skin that occur as a result of a primary lesion or a progression of a primary lesion. Examples of secondary lesions include crusts, ulcers, scales, and scars. This is why option B is the correct choice as it accurately describes the defining characteristic of secondary lesions. Options A, C, and D do not accurately describe secondary lesions. Option A is incorrect because secondary lesions do not develop in the early stages of a disease; they are subsequent changes to primary lesions. Option C describes primary lesions instead of secondary lesions, as secondary lesions are structural changes rather than changes in skin color. Option D is also incorrect as it describes pigmented lesions, which may be a type of primary lesion, but not specifically secondary lesions.